ACY1 Antibody

Polyclonal Antibody

ACY1

ACY 1 antibody, ACY-1 antibody, Acy1 antibody, ACY1_HUMAN antibody, ACY1D antibody, ACYLASE antibody, Acylase I antibody, Aminoacylase 1 antibody, Aminoacylase-1 antibody, EC 3.5.1.14 antibody, epididymis secretory protein Li 5 antibody, HEL-S-5 antibody, N acyl L amino acid amidohydrolase antibody, N-acyl-L-amino-acid amidohydrolase antibody, OTTHUMP00000212459 antibody, OTTHUMP00000212462 antibody, OTTHUMP00000212463 antibody, OTTHUMP00000212464 antibody, OTTHUMP00000212465 antibody

Fusion protein of human ACY1

This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.

Antigen Affinity Purified

Signal Transduction

Fusion protein of Human ACY1