IDH2 Antibody

Polyclonal Antibody

IDH2

D2HGA2 antibody, ICD-M antibody, IDH antibody, IDH2 antibody, IDHM antibody, IDHP_HUMAN antibody, IDP antibody, IDPM antibody, Isocitrate dehydrogenase [NADP], mitochondrial antibody, Isocitrate dehydrogenase 2 (NADP+), mitochondrial antibody, mNADP-IDH antibody, NADP(+)-specific ICDH antibody, Oxalosuccinate decarboxylase antibody

Fusion protein of human IDH2

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.

Antigen Affinity Purified

Signal Transduction

Fusion protein of Human IDH2