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PLEKHG6 Antibody

PLEKHG6 Antibody

Item no.	CSB-PA587894-50ul
Manufacturer	Cusabio
Amount	50 ul
Quantity options	100 ul 50 ul
Category	Neuroscience Neural Signaling Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot ELISA Primary Antibodies small GTPases Rho Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PLEKHG6 antibody; Pleckstrin homology domain-containing family G member 6 antibody; PH domain-containing family G member 6 antibody; Myosin-interacting guanine nucleotide exchange factor antibody; MyoGEF antibody
Similar products	pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	PLEKHG6
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species	Human
Immunogen	Fusion protein of human PLEKHG6
Dilution	ELISA:1:2000-1:5000 WB:1:500-1:2000 IHC:1:100-1:300
Background	PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
Buffer	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method	Antigen affinity purification
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Fusion protein of Human PLEKHG6
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 8/28/2025

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