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CACNA1C Antibody

CACNA1C Antibody

Item no.	CSB-PA615724LA01HU-50ug
Manufacturer	Cusabio
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry ELISA Immunofluorescence Cardiovascular Research Myocardial Infarction Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	alpha-1 polypeptide antibody,cardiac muscle antibody,isoform 1 antibody,L type antibody,CAC1C_HUMAN antibody,CACH 2 antibody,CACH2 antibody,CACN 2 antibody,CACN2 antibody,CACNA1C antibody,CACNL1A1 antibody,Calcium channel antibody,Calcium channel cardic dihydropyridine sensitive alpha 1 subunit antibody,Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle antibody,Calcium channel voltage dependent L type alpha 1C subunit antibody,CaV1.2 antibody,CCHL1A1 antibody,DHPR alpha 1 antibody,DHPR alpha 1 subunit antibody,LQT8 antibody,TS antibody,Voltage dependent L type calcium channel alpha 1C subunit antibody,Voltage dependent L type calcium channel subunit alpha 1C antibody,Voltage gated calcium channel alpha subunit Cav1.2 antibody,Voltage gated calcium channel subunit alpha Cav1.2 antibody,Voltage gated L type calcium channel Cav1.2 alpha 1 subunit,splice variant 10* antibody,Voltage-dependent L-type calcium channel subunit alpha-1C antibody,Voltage-gated calcium channel subunit alpha Cav1.2 antibody
Similar products	CACNA1C, isoform 1, L type, alpha-1 polypeptide, Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2), CACH2 CACN2 CACNL1A1 CCHL1A1
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:200-1:500
Manufacturer - Targets	CACNA1C
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	alpha-1 polypeptide antibody, cardiac muscle antibody, isoform 1 antibody, L type antibody, CAC1C_HUMAN antibody, CACH 2 antibody, CACH2 antibody, CACN 2 antibody, CACN2 antibody, CACNA1C antibody, CACNL1A1 antibody, Calcium channel antibody, Calcium channel cardic dihydropyridine sensitive alpha 1 subunit antibody, Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle antibody, Calcium channel voltage dependent L type alpha 1C subunit antibody, CaV1.2 antibody, CCHL1A1 antibody, DHPR alpha 1 antibody, DHPR alpha 1 subunit antibody, LQT8 antibody, TS antibody, Voltage dependent L type calcium channel alpha 1C subunit antibody, Voltage dependent L type calcium channel subunit alpha 1C antibody, Voltage gated calcium channel alpha subunit Cav1.2 antibody, Voltage gated calcium channel subunit alpha Cav1.2 antibody, Voltage gated L type calcium channel Cav1.2 alpha 1 subunit, splice variant 10* antibody, Voltage-dependent L-type calcium channel subunit alpha-1C antibody, Voltage-gated calcium channel subunit alpha Cav1.2 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Voltage-dependent L-type calcium channel subunit alpha-1C protein (1755-1971AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200 IF:1:200-1:500
Background	Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1C gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1C subunit play an important role in excitation-contraction coupling in the heart. The various isoforms display marked differences in the sensitivity to DHP compounds. Binding of calmodulin or CABP1 at the same regulatory sites results in an opposit effects on the channel function.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Neuroscience
Initial Research Areas	Neuroscience
Antigen Species	Human
Antigen	Recombinant Human Voltage-dependent L-type calcium channel subunit alpha-1C protein (1755-1971AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/18/2025

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