USP2 Antibody

Polyclonal Antibody

USP2

41 kDa ubiquitin specific protease antibody, 41 kDa ubiquitin-specific protease antibody, Deubiquitinating enzyme 2 antibody, Ubiquitin carboxyl terminal hydrolase 2 antibody, Ubiquitin carboxyl-terminal hydrolase 2 antibody, ubiquitin specific peptidase 2 antibody, Ubiquitin specific processing protease 2 antibody, Ubiquitin specific protease 12 antibody, Ubiquitin specific protease 9 antibody, Ubiquitin specific protease, 41kD antibody, Ubiquitin thioesterase 2 antibody, Ubiquitin thiolesterase 2 antibody, Ubiquitin-specific-processing protease 2 antibody, Ubiquitin-specific-processing protease testis antibody, UBP-t antibody, UBP2_HUMAN antibody, UBP41 antibody, USP2 antibody, USP9 antibody

Fusion protein of human USP2

This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Antigen Affinity Purified

Cell Biology

Fusion protein of Human USP2