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LRRK2 Antibody

LRRK2 Antibody

Item no.	CSB-PA722493LA01HU-50ug
Manufacturer	Cusabio
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Neuroscience Neuroinflammation Neural Mitochondrial Function Molecular Targets for Neuroscience Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	augmented in rheumatoid arthritis 17 antibody,AURA17 antibody,Dardarin antibody,Leucine rich repeat kinase 2 antibody,leucine rich repeat serine threonine protein kinase 2 antibody,Leucine-rich repeat serine/threonine-protein kinase 2 antibody,LRRK 2 antibody,LRRK2 antibody,LRRK2_HUMAN antibody,PARK 8 antibody,PARK8 antibody,RIPK7 antibody,ROCO 2 antibody,ROCO2 antibody
Similar products	LRRK2, PARK8, Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin)
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Manufacturer - Targets	LRRK2
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	augmented in rheumatoid arthritis 17 antibody, AURA17 antibody, Dardarin antibody, Leucine rich repeat kinase 2 antibody, leucine rich repeat serine threonine protein kinase 2 antibody, Leucine-rich repeat serine/threonine-protein kinase 2 antibody, LRRK 2 antibody, LRRK2 antibody, LRRK2_HUMAN antibody, PARK 8 antibody, PARK8 antibody, RIPK7 antibody, ROCO 2 antibody, ROCO2 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Leucine-rich repeat serine/threonine-protein kinase 2 protein (2029-2275AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200 IF:1:50-1:200
Background	Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). Plays a role in synaptic vesicle trafficking. Phosphorylates PRDX3. Has GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Neuroscience
Initial Research Areas	Neuroscience
Antigen Species	Human
Antigen	Recombinant Human Leucine-rich repeat serine/threonine-protein kinase 2 protein (2029-2275AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 11/6/2025

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