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NHLRC1 Antibody

NHLRC1 Antibody

Item no.	CSB-PA740936ESR2HU-50ul
Manufacturer	Cusabio
Amount	50 ul
Quantity options	100 ul 50 ul
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Immunofluorescence Autophagy Primary Antibodies By Organ Heart & Blood Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	bA204B7.2 antibody,E3 ubiquitin-protein ligase NHLRC1 antibody,EPM2A antibody,EPM2B antibody,EPM2B gene antibody,Malin antibody,MGC119262 antibody,MGC119264 antibody,MGC119265 antibody,NHL repeat containing 1 antibody,NHL repeat containing E3 ubiquitin protein ligase 1 antibody,NHL repeat containing protein 1 antibody,NHL repeat-containing protein 1 antibody,NHL repeat-containing protein 1 gene antibody,NHLC1_HUMAN antibody,NHLRC 1 antibody,Nhlrc1 antibody
Similar products	NHLRC1, EPM2B, E3 ubiquitin-protein ligase NHLRC1 (EC 2.3.2.27) (Malin) (NHL repeat-containing protein 1) (RING-type E3 ubiquitin transferase NHLRC1)
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:2000, IHC:1:1:20-1:200, IF:1:1:20-1:200
Manufacturer - Targets	NHLRC1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	bA204B7.2 antibody, E3 ubiquitin-protein ligase NHLRC1 antibody, EPM2A antibody, EPM2B antibody, EPM2B gene antibody, Malin antibody, MGC119262 antibody, MGC119264 antibody, MGC119265 antibody, NHL repeat containing 1 antibody, NHL repeat containing E3 ubiquitin protein ligase 1 antibody, NHL repeat containing protein 1 antibody, NHL repeat-containing protein 1 antibody, NHL repeat-containing protein 1 gene antibody, NHLC1_HUMAN antibody, NHLRC 1 antibody, Nhlrc1 antibody
Immunogen Species	Human
Immunogen	Recombinant Human E3 ubiquitin-protein ligase NHLRC1 protein (1-280AA)
Dilution	ELISA:1:2000-1:10000 WB:1:1000-1:5000 IHC:1:20-1:200
Background	E3 ubiquitin-protein ligase. Together with the phosphatase EPM2A/laforin, appears to be involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. In complex with EPM2A/laforin and HSP70, suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS). Ubiquitinates the glycogen-targeting protein phosphatase subunits PPP1R3C/PTG and PPP1R3D in a laforin-dependent manner and targets them for proteasome-dependent degradation, thus decreasing glycogen accumulation. Polyubiquitinates EPM2A/laforin and ubiquitinates AGL and targets them for proteasome-dependent degradation. Also promotes proteasome-independent protein degradation through the macroautophagy pathway.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	Antigen Affinity Purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Recombinant Human E3 ubiquitin-protein ligase NHLRC1 protein (1-280AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 1/22/2026

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