ARC Antibody

Polyclonal Antibody

ARC

activity regulated cytoskeleton associated protein antibody, activity regulated gene 3.1 protein homolog antibody, Activity-regulated cytoskeleton-associated protein antibody, Activity-regulated gene 3.1 protein homolog antibody, Arc antibody, ARC/ARG3.1 antibody, ARC_HUMAN antibody, Arg 3.1 antibody, Arg3.1 antibody

Fusion protein of human ARC

Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.

Antigen Affinity Purified

Neuroscience

Fusion protein of Human ARC