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MYLIP Antibody

MYLIP Antibody

Item no.	CSB-PA855506ESR2HU-50ul
Manufacturer	Cusabio
Amount	50 ul
Quantity options	100 ul 50 ul
Category	Neuroscience Neural Lineage Markers Aging & Neurological Disorders Antibodies Cell Biology Cell Status Necrosis Cytoskeleton Immunohistochemistry Western Blot ELISA Autophagy Motor proteins Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BM-023 antibody,BZF1 antibody,E3 ubiquitin protein ligase MYLIP antibody,E3 ubiquitin-protein ligase MYLIP antibody,Idol antibody,Inducible degrader of the LDL-receptor antibody,Lipoprotein receptor antibody,MIR antibody,MYLIP antibody,MYLIP_HUMAN antibody,Myosin regulatory light chain interacting protein antibody,PP5242 antibody
Similar products	MYLIP, E3 ubiquitin-protein ligase MYLIP (EC 2.3.2.27) (Inducible degrader of the LDL-receptor) (Idol) (Myosin regulatory light chain interacting protein) (MIR) (RING-type E3 ubiquitin transferase MYLIP), BZF1 IDOL
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Manufacturer - Targets	MYLIP
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	BM-023 antibody, BZF1 antibody, E3 ubiquitin protein ligase MYLIP antibody, E3 ubiquitin-protein ligase MYLIP antibody, Idol antibody, Inducible degrader of the LDL-receptor antibody, Lipoprotein receptor antibody, MIR antibody, MYLIP antibody, MYLIP_HUMAN antibody, Myosin regulatory light chain interacting protein antibody, PP5242 antibody
Immunogen Species	Human
Immunogen	Recombinant Human E3 ubiquitin-protein ligase MYLIP protein (266-445AA)
Dilution	ELISA:1:2000-1:10000 WB:1:1000-1:5000 IHC:1:20-1:200
Background	E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Antigen Affinity Purified
General Research Areas	Signal Transduction
Initial Research Areas	Signal Transduction
Antigen Species	Human
Antigen	Recombinant Human E3 ubiquitin-protein ligase MYLIP protein (266-445AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 12/18/2025

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