Comparison

PCGF1 Antibody, FITC conjugated

Item no. CSB-PA863114LC01HU-50ug
Manufacturer Cusabio
Amount 50 ug
Quantity options 100 ug 50 ug
Category
Type Antibody Polyclonal
Format Liquid
Applications ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag FITC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias PCGF1 antibody; NSPC1 antibody; RNF68 antibody; Polycomb group RING finger protein 1 antibody; Nervous system Polycomb-1 antibody; NSPc1 antibody; RING finger protein 68 antibody
Similar products PCGF1, Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68), NSPC1 RNF68
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Targets
PCGF1
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species
Human
Immunogen
Recombinant Human Polycomb group RING finger protein 1 protein (113-187AA)
Background
Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6, this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down-regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Regulates the expression of DPPA4 and NANOG in the NT2 embryonic carcinoma cells (PubMed:26687479).
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method
>95%, Protein G purified
General Research Areas
Cell Biology
Initial Research Areas
Cell Biology
Antigen Species
Human
Antigen
Recombinant Human Polycomb group RING finger protein 1 protein (113-187AA)
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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