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HIF1AN Antibody

HIF1AN Antibody

Item no.	CSB-PA865160LA01HU-50ug
Manufacturer	Cusabio
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Thyroid Cancer Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IP, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DKFZp762F1811 antibody,Factor inhibiting HIF-1 antibody,Factor inhibiting HIF1 antibody,FIH 1 antibody,FIH-1 antibody,FIH1 antibody,FLJ20615 antibody,FLJ22027 antibody,HIF1AN antibody,HIF1N_HUMAN antibody,Hypoxia inducible factor 1 alpha inhibitor antibody,Hypoxia inducible factor 1 alpha subunit inhibitor antibody,Hypoxia inducible factor asparagine hydroxylase antibody,Hypoxia-inducible factor 1-alpha inhibitor antibody,Hypoxia-inducible factor asparagine hydroxylase antibody,Peptide aspartate beta dioxygenase antibody
Similar products	HIF1AN, FIH1, Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase)
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000
Manufacturer - Targets	HIF1AN
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	DKFZp762F1811 antibody, Factor inhibiting HIF-1 antibody, Factor inhibiting HIF1 antibody, FIH 1 antibody, FIH-1 antibody, FIH1 antibody, FLJ20615 antibody, FLJ22027 antibody, HIF1AN antibody, HIF1N_HUMAN antibody, Hypoxia inducible factor 1 alpha inhibitor antibody, Hypoxia inducible factor 1 alpha subunit inhibitor antibody, Hypoxia inducible factor asparagine hydroxylase antibody, Hypoxia-inducible factor 1-alpha inhibitor antibody, Hypoxia-inducible factor asparagine hydroxylase antibody, Peptide aspartate beta dioxygenase antibody
Immunogen Species	Human
Immunogen	Recombinant Human Hypoxia-inducible factor 1-alpha inhibitor protein (2-254AA)
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:5000 IHC:1:20-1:200 IF:1:50-1:200 IP:1:200-1:2000
Background	Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively. Negatively regulates NOTCH1 activity, accelerating myogenic differentiation. Positively regulates ASB4 activity, promoting vascular differentiation.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human Hypoxia-inducible factor 1-alpha inhibitor protein (2-254AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/25/2025

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