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TCHP Antibody

TCHP Antibody

Item no.	CSB-PA874804LA01HU-50ug
Manufacturer	Cusabio
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Antibodies Cell Biology Cytoskeleton Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Intermediate filaments Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TCHP antibody,Trichoplein keratin filament-binding protein antibody,Protein TCHP antibody,Mitochondrial protein with oncostatic activity antibody,Mitostatin antibody,Tumor suppressor protein antibody
Similar products	TCHP, Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin) (Tumor suppressor protein)
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500
Manufacturer - Targets	TCHP
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species	Human
Immunogen	Recombinant Human Trichoplein keratin filament-binding protein (1-498AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200 IF:1:50-1:500
Background	Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Others
Antigen Species	Human
Antigen	Recombinant Human Trichoplein keratin filament-binding protein (1-498AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 11/20/2025

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