Comparison

FZD4 Antibody, FITC conjugated

Item no. CSB-PA890755LC01HU-50ug
Manufacturer Cusabio
Amount 50 ug
Quantity options 100 ug 50 ug
Category
Type Antibody Polyclonal
Format Liquid
Applications ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag FITC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CD 344 antibody; CD 344 antigen antibody; CD344 antibody; CD344 antigen antibody; EVR1 antibody; FEVR antibody; Frizzled (Drosophila) homolog 4 antibody; Frizzled 4 antibody; Frizzled family receptor 4 antibody; Frizzled homolog 4 (Drosophila) antibody; Frizzled-4 antibody; Fz 4 antibody; Fz-4 antibody; Fz4 antibody; FZD4 antibody; FZD4_HUMAN antibody; FZD4S antibody; FzE4 antibody; GPCR antibody; hFz4 antibody; MGC34390 antibody; WNT receptor frizzled 4 antibody
Similar products FZD4, Frizzled-4 (Fz-4) (hFz4) (FzE4) (CD antigen CD344)
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Targets
FZD4
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
CD 344 antibody; CD 344 antigen antibody; CD344 antibody; CD344 antigen antibody; EVR1 antibody; FEVR antibody; Frizzled (Drosophila) homolog 4 antibody; Frizzled 4 antibody; Frizzled family receptor 4 antibody; Frizzled homolog 4 (Drosophila) antibody; Frizzled-4 antibody; Fz 4 antibody; Fz-4 antibody; Fz4 antibody; FZD4 antibody; FZD4_HUMAN antibody; FZD4S antibody; FzE4 antibody; GPCR antibody; hFz4 antibody; MGC34390 antibody; WNT receptor frizzled 4 antibody
Immunogen Species
Human
Immunogen
Recombinant Human Frizzled-4 protein (37-222AA)
Background
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin (CTNNB1) and activation of Wnt target genes. Plays a critical role in retinal vascularization by acting as a receptor for Wnt proteins and norrin (NDP). In retina, it can be both activated by Wnt protein-binding, but also by a Wnt-independent signaling via binding of norrin (NDP), promoting in both cases beta-catenin (CTNNB1) accumulation and stimulation of LEF/TCF-mediated transcriptional programs. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method
>95%, Protein G purified
General Research Areas
Signal Transduction
Initial Research Areas
Signal Transduction
Antigen Species
Human
Antigen
Recombinant Human Frizzled-4 protein (37-222AA)
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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