RAB23 Antibody

Polyclonal Antibody

RAB23

DKFZp781H0695 antibody, HSPC137 antibody, MGC8900 antibody, Rab 23 antibody, RAB family small GTP binding protein RAB 23 antibody, Rab23 antibody, RAB23, member RAS oncogene family antibody, RAB23_HUMAN antibody, Ras related protein Rab 23 antibody, Ras-related protein Rab-23 antibody

Recombinant Human Ras-related protein Rab-23 protein (1-237AA)

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.

Antigen Affinity Purified

Neuroscience

Recombinant Human Ras-related protein Rab-23 protein (1-237AA)