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PIAS3 Antibody

PIAS3 Antibody

Manufacturer	Cusabio
Category	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Obesity Immunohistochemistry ELISA Enzymes Fatty Acid Synthesis Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Format	Liquid
Applications	IHC, ELISA
Amount	50ul
Host	Rabbit
Item no.	CSB-PA896765DSR1HU-50ul
Targets	SOAT1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Immunogen Species	Human
UniprotID	Q9Y6X2
Immunogen	Recombinant Human E3 SUMO-protein ligase PIAS3 protein (399-628AA)
Applications info	ELISA, IHC, Recommended dilution: IHC:1:20-1:200
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	IHC:1:20-1:200
Background	Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.
Conjugate	Non-conjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	Antigen Affinity Purified
General Research Areas	Epigenetics and Nuclear Signaling, Cell biology
Initial Research Areas	Cell Biology

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CSB-PA896765DSR1HU-50ul-datasheet.pdf

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Amount: 50ul

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Delivery expected until 5/30/2024