LEPR Antibody

Polyclonal Antibody

LEPR

CD 295 antibody, CD295 antibody, CD295 antigen antibody, Db antibody, Fa antibody, HuB219 antibody, LEP R antibody, LEP-R antibody, LEPR antibody, LEPR_HUMAN antibody, LEPRD antibody, Leptin receptor antibody, Leptin receptor fatty antibody, Leptin receptor gene related protein antibody, Leptin receptor precursor antibody, Leptin receptor precursor antibody, OB R gene related protein antibody, OB receptor antibody, OB-R antibody, OB-RGRP antibody, obl antibody, Obr antibody

Synthetic peptide of human LEPR

The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).

Antigen Affinity Purified

Signal Transduction

Synthetic peptide of Human LEPR