RASA4 Antibody

ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:10-1:50

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Fusion protein of human RASA4

This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [

Antigen Affinity Purified

Signal Transduction

Fusion protein of Human RASA4