ABI1 Antibody

Polyclonal Antibody

ABI1

Abelson interactor 1 antibody, Abi-1 antibody, Abi1 antibody, ABI1_HUMAN antibody, Abl binding protein 4 antibody, Abl interactor 1 antibody, Abl interactor protein 1 antibody, Abl-binding protein 4 antibody, AblBP4 antibody, e3B1 antibody, Eps8 binding protein antibody, Eps8 SH3 domain binding protein antibody, Eps8 SH3 domain-binding protein antibody, Eps8-binding protein antibody, Hssh3bp1 antibody, Interactor protein AblBP4 antibody, NAP1 antibody, Nap1 binding protein antibody, Nap1-binding protein antibody, Nap1BP antibody, Spectrin SH3 domain binding protein 1 antibody, Spectrin SH3 domain-binding protein 1 antibody, SSH3BP antibody

Synthetic peptide of human ABI1

This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10, 11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14

Antigen Affinity Purified

Cell Biology

Synthetic peptide of Human ABI1