Comparison

SMURF2 Antibody

Item no. CSB-PA967268-50ul
Manufacturer Cusabio
Amount 50 ul
Quantity options 100 ul 50 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias E3 ubiquitin-protein ligase SMURF2 antibody,EC 6.3.2. antibody,hSMURF2 antibody,MGC138150 antibody,Smad specific E3 ubiquitin ligase 2 antibody,SMAD specific E3 ubiquitin protein ligase 2 antibody,SMAD ubiquitination regulatory factor 2 antibody,SMAD-specific E3 ubiquitin-protein ligase 2 antibody,SMUF2_HUMAN antibody,Smurf2 antibody,Ubiquitin protein ligase SMURF2 antibody
Similar products SMAD specific E3 ubiquitin protein ligase 2
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100
Manufacturer - Targets
SMURF2
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias
E3 ubiquitin-protein ligase SMURF2 antibody, EC 6.3.2. antibody, hSMURF2 antibody, MGC138150 antibody, Smad specific E3 ubiquitin ligase 2 antibody, SMAD specific E3 ubiquitin protein ligase 2 antibody, SMAD ubiquitination regulatory factor 2 antibody, SMAD-specific E3 ubiquitin-protein ligase 2 antibody, SMUF2_HUMAN antibody, Smurf2 antibody, Ubiquitin protein ligase SMURF2 antibody
Immunogen Species
Human
Immunogen
Synthetic peptide of human SMURF2
Dilution
ELISA:1:1000-1:2000
IHC:1:25-1:100
Background
E3 ubiquitin-protein ligase SMURF2 is an enzyme that in humans is encoded by the SMURF2 gene. E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation. In addition, interaction with SMAD7 activates autocatalytic degradation, which is prevented by interaction with SCYE1. Forms a stable complex with the TGF-beta receptor-mediated phosphorylated SMAD2 and SMAD3.
Buffer
pH7.4 of PBS, 0.05% NaN3, 40% Glycerol.
Purification Method
Antigen Affinity Purified
General Research Areas
Epigenetics and Nuclear Signaling
Initial Research Areas
Epigenetics and Nuclear Signaling
Antigen Species
Human
Antigen
Synthetic peptide of Human SMURF2
Clonality
Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
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