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CDKN1B Recombinant Monoclonal Antibody

CDKN1B Recombinant Monoclonal Antibody

Item no.	CSB-RA005087A0HU
Manufacturer	Cusabio
Amount	100 ul
Quantity options	100 ul 50 ul
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Immunofluorescence Senescence Proliferation Primary Antibodies By Organ Lung Cancer Bladder Cancer Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Clone	1G2
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cyclin-dependent kinase inhibitor 1B,Cyclin-dependent kinase inhibitor p27,CDKN1B,KIP1
Similar products	CDKN1B, KIP1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27
Available
Manufacturer - Type	Recombinant Antibody
Manufacturer - Applications	ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Targets	CDKN1B
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen	A synthesized peptide derived from human CDKN1B
Dilution	WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200
Background	Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA (PubMed:28666995). Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Buffer	Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Purification Method	Affinity-chromatography
General Research Areas	Cell Biology
Modified	Cell Biology
Antigen Species	Human
Antigen	A synthesized peptide derived from human CDKN1B
Clonality	Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/22/2026

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