« Back
Home /
Phospho-Histone H2AX (S139) Recombinant Monoclonal Antibody

Phospho-Histone H2AX (S139) Recombinant Monoclonal Antibody

Item no.	CSB-RA010097A139phHU-50ul
Manufacturer	Cusabio
Amount	50 ul
Quantity options	100 ul 50 ul
Category	Neuroscience Neural Epigenetics Antibodies Western Blot ELISA Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ELISA
Clone	1F10
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Histone H2AX, H2a/x, Histone H2A.X, H2AFX, H2AX
Similar products	H2AFX, H2AX, H2a/x, Histone H2AX, Histone H2A.X
Available
Manufacturer - Type	Recombinant Antibody
Manufacturer - Applications	ELISA, WB; Recommended dilution: WB:1:3000-1:10000
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Targets	H2AFX
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen	A synthesized peptide
Dilution	WB:1:3000-1:10000
Background	Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Affinity-chromatography
General Research Areas	Epigenetics and Nuclear Signaling
Modified	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	A synthesized peptide
Clonality	Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CSB-RA010097A139phHU-50ul-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 50 ul

available

Delivery expected until 10/16/2025

Express Delivery: Save 3 days

Compare

Add to wishlist

Get an offer