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HNRNPK Recombinant Monoclonal Antibody

HNRNPK Recombinant Monoclonal Antibody

Item no.	CSB-RA010611A0HU-50ul
Manufacturer	Cusabio
Amount	50 ul
Quantity options	100 ul 50 ul
Category	Oncology Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Lung Cancer
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IP, IHC, ELISA
Clone	3G7
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Heterogeneous nuclear ribonucleoprotein K, hnRNP K, Transformation up-regulated nuclear protein, TUNP, HNRNPK, HNRPK
Similar products	HNRNPK, HNRPK, hnRNP K, TUNP, Transformation up-regulated nuclear protein, Heterogeneous nuclear ribonucleoprotein K
Available
Manufacturer - Type	Recombinant Antibody
Manufacturer - Applications	ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Targets	HNRNPK
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen	A synthesized peptide derived from human HNRNPK
Dilution	WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
Background	One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Affinity-chromatography
General Research Areas	Epigenetics and Nuclear Signaling
Modified	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	A synthesized peptide derived from human HNRNPK
Clonality	Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ul

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Delivery expected until 9/11/2025

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