Comparison

CDC42 Recombinant Monoclonal Antibody

Item no. CSB-RA177985A0HU-50ul
Manufacturer Cusabio
Amount 50 ul
Quantity options 100 ul 50 ul
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, IHC, ELISA
Clone 3C3
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Cell division control protein 42 homolog (G25K GTP-binding protein), CDC42
Similar products CDC42, Cell division control protein 42 homolog (G25K GTP-binding protein)
Available
Manufacturer - Type
Recombinant Antibody
Manufacturer - Applications
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200
Manufacturer - Isotype
Rabbit IgG
Manufacturer - Targets
CDC42
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen
A synthesized peptide derived from human CDC42
Dilution
WB:1:500-1:5000, IHC:1:50-1:200
Background
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration. Required for DOCK10-mediated spine formation in Purkinje cells and hippocampal neurons. Facilitates filopodia formation upon DOCK11-activation (By similarity).
Buffer
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method
Affinity-chromatography
General Research Areas
Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction
Modified
Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction
Antigen Species
Human
Antigen
A synthesized peptide derived from human CDC42
Clonality
Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ul
Available: In stock
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