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CD22 Recombinant Monoclonal Antibody

CD22 Recombinant Monoclonal Antibody

Item no.	CSB-RA962691A0HU-100ul
Manufacturer	Cusabio
Amount	100 ul
Quantity options	100 ul 50 ul
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Movement Cell Adhesion Immunohistochemistry ELISA Primary Antibodies Progenitor Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	IHC, ELISA
Clone	3D8
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22), CD22, SIGLEC2
Similar products	CD22, SIGLEC2, B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)
Available
Manufacturer - Type	Recombinant Antibody
Manufacturer - Applications	ELISA, IHC; Recommended dilution: IHC:1:50-1:200
Manufacturer - Isotype	Rabbit IgG
Manufacturer - Targets	CD22
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen	A synthesized peptide derived from human CD22
Dilution	IHC:1:50-1:200
Background	Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	Affinity-chromatography
General Research Areas	Cancer; Immunology; Stem cells
Modified	Cancer; Immunology; Stem cells
Antigen Species	Human
Antigen	A synthesized peptide derived from human CD22
Clonality	Monoclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 8/21/2025

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