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Anti-CTLA-4 antibody(DM50); Rabbit mAb

Anti-CTLA-4 antibody(DM50); Rabbit mAb

Item no.	DIM-DME100049-10uL
Manufacturer	DIMA Biotechnology
Amount	10 uL
Quantity options	100 uL 100 ug 10 uL 10 ug 500 ug
Category	Oncology Antibodies By Cell Type Carcinoma Flow Cytometry ELISA Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	FC, ELISA
Clone	DM50
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CTLA4,CD152
Shipping Condition	Room temperature
Available
Manufacturer - Category	Monoclonal antibodies
Manufacturer - Targets	CTLA-4
Molecular Weight	24.6 kDa
Buffer	50% Glycerol; PBS, pH 7.4; 0.1% BSA
Clonality	Monoclonal
Purification	Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions	ELISA 1:5000-10000; Flow Cyt 1:100
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain; a transmembrane domain; and a cytoplasmic tail. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond; while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus; Graves disease; Hashimoto thyroiditis; celiac disease; systemic lupus erythematosus; thyroid-associated orbitopathy; and other autoimmune diseases.
Immunogen	Recombinant human CTLA4(Gln36-Ser161) (PME100017) produced by using human HEK293 cells
Antigen	CTLA4
Application Advice	ELISA 1/5000-10000; Flow Cyt 1/100
Description	Anti-CTLA-4 antibody(DM50); Rabbit mAb
Preservative	0.1% Procline 300
Reconstitution	Reconstitute with deionized water
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage	Research use only

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 uL

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Delivery expected until 10/30/2025

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