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anti- BAX antibody

anti- BAX antibody

Manufacturer	FineTest
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Specific against	Human, Mouse, Rat
Isotype	IgG
Format	liquid
Amount	100ug
Host	Rabbit
Item no.	FNab00809-100ug
eClass 6.1	32160702
eClass 9.0	32160702
Available
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Clonality	polyclonal
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20C for 12 months (Avoid repeated freeze / thaw cycles.)
Background	The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Immunogen	BCL2-associated X protein
Observed MW	21 kDa
Uniprot ID	Q07812
Tested Application	ELISA, WB, IHC, IF
Recommended dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200
Gene ID	581
Research Area	Neuroscience, Cancer, Developmental biology

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 8/2/2023