Item no. |
FNab00809-100ug |
Manufacturer |
FineTest
|
Amount |
100 ug |
Quantity options |
100 ug
100 ug
100 ug
100 ug
|
Category |
|
Type |
Antibody Monoclonal |
Format |
Liquid |
Applications |
WB, IF, IHC, ELISA |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Purity |
≥95% as determined by SDS-PAGE |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Apoptosis regulator BAX,Bcl-2-like protein 4 (Bcl2-L-4),BAX,BCL2L4 |
Available |
|
Manufacturer - Targets |
BAX |
Storage Conditions |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.) |
Background |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. |
Clonality |
polyclonal |
Immunogen |
BCL2-associated X protein |
Observed MW |
21 kDa |
Purification |
Immunogen affinity purified |
Recommended dilution |
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200 |
Manufacturer - Research Area |
Neuroscience, Cancer, Developmental biology |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.