Comparison

BEST1 antibody

Item no. FNab00865-100ug
Manufacturer FineTest
Amount 100 ug
Quantity options 100 ug 100 ug
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Purity ≥95% as determined by SDS-PAGE
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Bestrophin-1,TU15B,Vitelliform macular dystrophy protein 2,BEST1,VMD2
Available
Manufacturer - Targets
BEST1
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
Clonality
polyclonal
Immunogen
bestrophin 1
Observed MW
70 kDa
Purification
Immunogen affinity purified
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Manufacturer - Research Area
Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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