Comparison

anti- BRD8 antibody

Manufacturer FineTest
Category
Type Antibody Monoclonal
Specific against Human
Clone 4B2
Isotype IgG1
Format liquid
Amount 100ug
Host Mouse
Item no. FNab00950-100ug
eClass 6.1 32160702
eClass 9.0 42030590
Available
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Clonality
monoclonal
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20C for 12 months(Avoid repeated freeze / thaw cycles.)
Background
May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors(NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase(HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
Immunogen
bromodomain containing 8
Observed MW
120 kDa
Uniprot ID
Q9H0E9
Tested Application
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Gene ID
10902
Research Area
Signal Transduction, Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
available

Delivery expected until 6/27/2024 

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