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Bulk Anti-Human CD56 (ERIC-1) Antibody

Bulk Anti-Human CD56 (ERIC-1) Antibody

Item no.	ICH1015-50MG
Manufacturer	IchorBio
Amount	50 mg
Quantity options	0.5 mg 100 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Neural Adhesion Molecules Antibodies In Vivo Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Myeloma Sarcoma Adenocarcinoma Immunohistochemistry Western Blot ELISA By Organ Lung Cancer
Type	Antibody
Applications	WB, IP, IHC, ELISA, Dot
Clone	ERIC-1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Neural cell adhesion molecule 1, NCAM1
Shipping condition	Cool pack
Available
Specificity	Anti-CD56 In Vivo Antibody - Low Endotoxin (ERIC-1) recognizes Human CD56. Anti-Human CD56 recognizes the (Mr 180, 145, 125 kDa) isoforms of the human neural cell adhesion molecule (NCAM)
Manufacturer - Applications	ELISA Capture, IHC (Frozen), IHC (Paraffin), Western Blot, Immunoprecipitation, Dot Blot
Manufacturer - Category	Low Endotoxin, anti-human, monoclonal antibody
Manufacturer - Isotype	Mouse IgG1
Manufacturer - Targets	CD56
Shipping Temperature	Blue ice
Storage Conditions	anti-CD56 In Vivo Antibody - Low Endotoxin (ERIC-1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Aggregation	Aggregation level ≤ 5%
Formulation	0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution	The CD56 (NCAM) antigen is expressed on most neuroectodermal derived cell lines, tissues, and tumors. NCAM is also known to be expressed on some mesodermally derived tissues such as muscle and on natural killer (NK) lymphocytes. The binding of ERIC-1 to both normal and neoplastic tissue is lost when tissues are conventionally fixed in formalin and embedded in paraffin. The epitope was preserved when exposed to dehydrating fixatives such as cold acetone (-20EC) for 5 min. CD56 is present on 10-25% of peripheral blood lymphocytes.
Application Notes	ELISA Sandwich: This antibody is useful as the capture antibody in a sandwich ELISA. The suggested coating concentration is 80 ng/mL. Dot Blots: Immunoblotting: Recognizes 120, 140, and 180 kDa NCAM isoforms. Each investigator should determine their own optimal working dilution for specific applications.
Background	Anti-Human CD56 can be used in studies of the neural cell adhesion molecule. This antibody may also be used to study isoforms of NCAM expressed on different tumor types. Anti-CD56 (clone ERIC-1) works well in western blot for analysis of isoforms expressed. Anti-CD56 did not react with any of the leukemias or lymphomas tested
Concentration	1.0 - 5.0 mg/ml
Endotoxin	<0.5 EU/mg as determined by the LAL method
Manufacturer - Specificity	Anti-CD56 In Vivo Antibody - Low Endotoxin (ERIC-1) recognizes Human CD56. Anti-Human CD56 recognizes the (Mr 180, 145, 125 kDa) isoforms of the human neural cell adhesion molecule (NCAM)
Purification method	This monoclonal antibody was purified using Protein A
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen	Human Retinoblastoma tumor
Isotype Control	Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
Buffer	ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 7/31/2025

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