Comparison

Anti-Mouse CD115 In Vivo Antibody - Low Endotoxin (AFS98) European Partner

Manufacturer IchorBio
Category
Type Antibody
Specific against Mouse
Clone AFS98
Isotype IgG2a Kappa
Applications WB, Blocking
Amount 1mg
Host Rat
Item no. ICH1068-1MG
Targets CSF1R
eClass 6.1 32160702
eClass 9.0 32160702
Available
Aggregation
Aggregation level <= 5%
Antigen Distribution
Monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, osteoclasts
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Background
Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.
Concentration
1.0 - 5.0 mg/ml
Endotoxin
<= 1.0 EU/mg as determined by the LAL method
Formulation
0.01 M phosphate buffered saline (PBS), pH 7.2 - 7.4 without azide or BSA.
Immunogen
Purified Recombinant Mouse M-CSFR
Product Type
Low Endotoxin, anti-mouse
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Storage
anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) is stable when stored at 2-8C. For long term storage aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles. and keep sterile.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1mg
Available: In stock
available

Delivery expected until 6/20/2024 

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