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Anti-Mouse Ly-6G/Ly-6C In Vivo Antibody - Ultra Low Endotoxin (RB6-8C5)

Anti-Mouse Ly-6G/Ly-6C In Vivo Antibody - Ultra Low Endotoxin (RB6-8C5)

Manufacturer	IchorBio
Category	In Vivo Antibodies In Vivo Antibodies Flow Cytometry Western Blot
Type	Antibody
Specific against	Mouse
Clone	RB6-8C5
Isotype	IgG2b
Applications	WB, FC, IP, IHC, ICC, FA
Amount	5mg
Host	Rat
Item no.	ICH1131UL-5MG
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Ultra-Low Endotoxin, anti-mouse
Target Information	Ly-6G/Ly-6C
Isotype Information	Rat IgG2b
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution	The Gr-1 antigen is present at various levels correlated with granulocyte differentiation and maturation. The Gr-1 antigen is expressed on other myeloid populations, but not on lymphoid or erythroid cells.
Background	Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. Clone RB6-8C5 antibody has been shown to inhibit the binding of the clone 1A8 antibody. Clone 1A8 monoclonal antibody reacts specifically with mouse Ly6G with no reported cross-reactivity with Ly6C.
Immunogen	Raised against granulocytes of mouse origin
Concentration	0.5 mg/ml
Formulation	No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl.
Endotoxin	≤ 0.5 EU/mg as determined by the LAL method
Aggregation	Aggregation level ≤ 1%
IMPACT Pathogen Test	We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for: - Mycoplasma spp - Mycoplasma pulmonis - Pneumonia virus of mice - Kilham's rat virus - Toolan's H1 virus - Rat parvovirus - Lymphocytic choriomeningitis virus - Rat cytomegalovirus - Sendai virus - Rat coronavirus - Sialodacryoadenitis virus - Rat minute virus - Seoul virus - Mouse adenovirus - Reovirus 3 - Rat theilovirus
Storage	anti-Ly-6G/Ly-6C In Vivo Antibody - Ultra Low Endotoxin (RB6-8C5) is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

available

Delivery expected until 5/16/2024