Manufacturer |
IchorBio
|
Category |
|
Type |
Antibody |
Specific against |
Mouse |
Clone |
TR75-54.7 |
Isotype |
IgG |
Applications |
WB, FC, IP, ELISA, Blocking |
Amount |
25mg |
Host |
Hamster - Armenian |
Item no. |
ICH1137-25MG |
Targets |
TNFRSF1B |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Manufacturers Product Category |
Low Endotoxin, anti-mouse |
Target Information |
TNFR2 |
Isotype Information |
Armenian Hamster IgG |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Background |
Tumor necrosis factor receptor II (TNF-RII) is present on most cell types and is considered to play a prominent role in stimulation by TNF-alpha. TNFRII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocytes and mast cells. It is expressed by a variety of other cell types including endothelial cells, cardiac myocytes and prostate cells |
Immunogen |
Purified Recombinant Mouse TNF R2 |
Concentration |
1.0 mg/ml |
Formulation |
0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Aggregation |
Aggregation level ≤ 5% |
Storage |
anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long-term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Application Notes |
Blocking: Clone TR75-54.7 antibody has been reported to block ligand-induced receptor signaling. - Each investigator should determine their own optimal working dilution for specific applications. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.