Item no. |
ICH1137-5MG |
Manufacturer |
IchorBio
|
Amount |
5 mg |
Quantity options |
100 mg
1 mg
25 mg
50 mg
5 mg
|
Category |
|
Type |
Antibody |
Applications |
WB, FC, IP, ELISA, Blocking |
Clone |
TR75-54.7 |
Specific against |
Mouse (Murine, Mus musculus) |
Host |
Hamster - Armenian |
Isotype |
IgG |
Purity |
>95% by SDS-PAGE and HPLC |
Citations |
Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Tnfrsf1b, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b, Tnfr-2 |
Shipping condition |
Cool pack |
Available |
|
Specificity |
Anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) recognizes Mouse CD120 |
Manufacturer - Applications |
Immunoprecipitation, Western Blot, Blocking, Flow Cytometry, ELISA |
Manufacturer - Category |
Low Endotoxin, anti-mouse, monoclonal antibody |
Manufacturer - Isotype |
Armenian Hamster IgG |
Manufacturer - Targets |
TNFR2 |
Shipping Temperature |
Blue ice |
Storage Conditions |
anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long-term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Aggregation |
Aggregation level ≤ 5% |
Formulation |
0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
Application Notes |
Blocking: Clone TR75-54.7 antibody has been reported to block ligand-induced receptor signaling. Each investigator should determine their own optimal working dilution for specific applications. |
Background |
Tumor necrosis factor receptor II (TNF-RII) is present on most cell types and is considered to play a prominent role in stimulation by TNF-alpha. TNFRII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocytes and mast cells. It is expressed by a variety of other cell types including endothelial cells, cardiac myocytes and prostate cells |
Concentration |
1.0 mg/ml |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Manufacturer - Specificity |
Anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) recognizes Mouse CD120 |
Purification method |
This monoclonal antibody was purified using Protein A |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Immunogen |
Purified Recombinant Mouse TNF R2 |
Isotype Control |
Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251) |
Buffer |
ICH3001-100ml; ICH3002-100ml; ICH3003-100ml |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.