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Anti-Human AITRL - 25 µg

Anti-Human AITRL - 25 µg

Item no.	LEIN-A333-25ug
Manufacturer	Leinco Technologies
Amount	25 ug
Quantity options	100 ug 25 ug
Category	Antibodies Flow Cytometry Western Blot Primary Antibodies
Type	Antibody Primary
Applications	WB, FC, other
Specific against	Human (Homo sapiens)
Host	Caprine
NCBI	8995
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	B, CyTOF®, FC, WB
Manufacturer - Category	Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets	AITRL
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	Tumor necrosis factor (ligand) superfamily, member 18, also known as TNFSF18 and AITRL, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
Background	Tumor necrosis factor (ligand) superfamily, member 18, also known as TNFSF18 and AITRL, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
Other Applications Reported In Literature	Blocking: In a functional ELISA, < 5 µg/mL of this antibody will block 50% of the binding of 10 ng/mL of biotinylated Recombinant Human GITR Ligand/TNFSF18 to immobilized Recombinant Human GITR/TNFRSF18 Fc Chimera coated at 2 µg/mL (100 µL/well). At 50 μg/mL, this antibody will block > 90% of the binding. CyTOF-ready:Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
PubMed	AITRL
Manufacturer - Specificity	Rabbit Anti-Human AITRL (TNFSF18) recognizes Human TNFSF18. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2828103
Formulation	This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Immunogen	Purified Recombinant Human AITRL/TNFSF18 (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, AITRL, Activation-induced TNFR member Ligand, TNFSF18, GITRL, TNFSF18, Human AITRL, Anti-Human AITRL

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-A333-25ug-safety-datasheet.pdf