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Anti-Mouse Vγ 3 (TCR) - PE

Anti-Mouse Vγ 3 (TCR) - PE

Item no.	LEIN-T136-200ug
Manufacturer	Leinco Technologies
Amount	200 ug
Quantity options	100 ug 200 ug 50 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Clone	536
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Syrian
Citations	Havran, et al. (1989) Pro. Natl. Acad. Sci. USA 86:4185
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Shipping Condition	Cool pack
Available
Manufacturer - Category	Mouse T-Cell Receptor Complex
Manufacturer - Targets	Vγ 3 T-Cell Receptor
Country of Origin	USA
Shipping Temperature	Next Day 2-8°C
Storage Conditions	This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Background	The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
PubMed	Vγ 3 T-Cell Receptor
Excitation Laser	Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Manufacturer - Research Area	Adaptive Immunity, Immunology
Manufacturer - Specificity	Anti-Mouse Vγ 3 TCR antibody recognizes an epitope of the variable region (Vγ 3) gene product. Antibody from clone 536 immunoprecipitates the TCR heterodimer with two subunits of apparent molecular mass of 52 and 42 kDa.
RRID	AB_2894345
Concentration	0.2 mg/ml
Formulation	This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	The antibody 536 stained less than 1% of cells in adult thymus (AKR), splenocytes, lymph node, adult CD4-8- thymocytes, and adult CD4-8-, T splenocyte. 92% of day 14 old BALB/C fetal thymus, 86% of C57BL/6 dEC (Thy-1+) and 94% of AKR dEC (Thy-1+) stained positive using this antibody.
Immunogen	AKR mouse dendritic epidermal cell clone 7-17
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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LEIN-T136-200ug-safety-datasheet.pdf