Comparison

Anti-Mouse Vγ 3 (TCR) - PE

Item no. LEIN-T136-200ug
Manufacturer Leinco Technologies
Amount 200 ug
Quantity options 100 ug 200 ug 50 ug
Category
Type Antibody Primary
Clone 536
Specific against Mouse (Murine, Mus musculus)
Host Hamster - Syrian
Citations Havran, et al. (1989) Pro. Natl. Acad. Sci. USA 86:4185
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Shipping Condition Cool pack
Available
Manufacturer - Category
Mouse T-Cell Receptor Complex
Manufacturer - Targets
Vγ 3 T-Cell Receptor
Country of Origin
USA
Shipping Temperature
Next Day 2-8°C
Storage Conditions
This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Background
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
PubMed
Vγ 3 T-Cell Receptor
Excitation Laser
Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Manufacturer - Research Area
Adaptive Immunity, Immunology
Manufacturer - Specificity
Anti-Mouse Vγ 3 TCR antibody recognizes an epitope of the variable region (Vγ 3) gene product. Antibody from clone 536 immunoprecipitates the TCR heterodimer with two subunits of apparent molecular mass of 52 and 42 kDa.
RRID
AB_2894345
Concentration
0.2 mg/ml
Formulation
This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution
The antibody 536 stained less than 1% of cells in adult thymus (AKR), splenocytes, lymph node, adult CD4-8- thymocytes, and adult CD4-8-, T splenocyte. 92% of day 14 old BALB/C fetal thymus, 86% of C57BL/6 dEC (Thy-1+) and 94% of AKR dEC (Thy-1+) stained positive using this antibody.
Immunogen
AKR mouse dendritic epidermal cell clone 7-17
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 ug
Available: In stock
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