PAFAH1B1 Antibody

Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies

PAFAH1B1

Liquid

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq

https://www.ncbi.nlm.nih.gov/protein/NP_000421

Monoclonal

In 1x PBS, pH 7.4