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GZMA Antibody (OACA06883)

GZMA Antibody (OACA06883)

Item no.	OACA06883
Manufacturer	AVIVA Systems Biology
Amount	50ul
Category	Antibodies Immunohistochemistry Primary Antibodies
Type	Antibody Polyclonal
Applications	IHC
Specific against	other
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Gene symbol	GZMA
Protein name	Granzyme A
Product format	Liquid
Gene id	3001
Reconstitution and storage	Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
Description of target	Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
Purification	Antigen Affinity Purified
Clonality	Polyclonal
Formulation	PBS with, 50% glycerol, pH7.3.
Immunogen	Recombinant human Granzyme A protein (29-262AA)
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 9/11/2025

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