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PDE6B antibody - N-terminal region (ARP63581_P050)

PDE6B antibody - N-terminal region (ARP63581_P050)

Manufacturer	AVIVA Systems Biology
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human, Mouse, Rat, Rabbit, Fish, Guinea Pig, Bovine, Canine, Equine
Format	Lyophilized powder
Applications	WB
Amount	100ul
Host	Rabbit
Item no.	ARP63581_P050
eClass 6.1	32160702
eClass 9.0	32160702
Available
Gene symbol	PDE6B
Protein name	Rod cGMP-specific 3', 5'-cyclic phosphodiesterase subunit beta
Protein size	575
Molecular weight	63kDa
Subunit	beta
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id	5158
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	PPP1CC.
Description of target	Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Homology	Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Purification	Affinity Purified
Clonality	Polyclonal
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

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Delivery expected until 5/30/2024