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FOXO4 Antibody

FOXO4 Antibody

Item no.	OAAF01175
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Metabolism Diabetes Antibodies By Cell Type Carcinoma Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies By Organ Skin Cancer Immunostaining Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Monkey (Cynomolgus, Simian)
Host	Rabbit
Citations	Peters U., Hum. Genet. 100:569-572(1997). Borkhardt A., Oncogene 14:195-202(1997). Yang Z., J. Biol. Chem. 277:8068-8075(2002).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AFX;AFX1;fork head domain transcription factor AFX1;forkhead box protein O4;MLLT7;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog,Drosophila); translocated to,7.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	53 kDa
Manufacturer - Application Additional Information	WB: 1:500~1:3000; IF: 1:100~1:500; ELISA: 1:20000
Gene symbol	FOXO4
Gene Fullname	forkhead box O4
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Protein accession_num	NP_001164402.1
Protein name	Forkhead box protein O4
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human FOXO4.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	FOXO4 (Ab-451) antibody detects endogenous levels of total FOXO4 protein
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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