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HtrA2 Antibody

HtrA2 Antibody

Item no.	OAAF01638
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Neuroscience Aging & Neurological Disorders Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Faccio L., J. Biol. Chem. 275:2581-2588(2000). Gray C.W., Eur. J. Biochem. 267:5699-5710(2000). Faccio L., Genomics 68:343-347(2000).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	epididymis secretory sperm binding protein;high temperature requirement protein A2;HtrA-like serine protease;MGCA8;OMI;Omi stress-regulated endoprotease;PARK13;protease,serine,25;PRSS25;serine protease 25;serine protease HTRA2,mitochondrial;serine proteinase OMI.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	48 kDa
Manufacturer - Application Additional Information	IHC: 1:50~1:100; ELISA: 1:40000
Gene symbol	HTRA2
Gene Fullname	HtrA serine peptidase 2
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
Protein accession_num	NP_037379.1
Protein name	Serine protease HTRA2, mitochondrial
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human HtrA2.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	HtrA2 antibody detects endogenous levels of total HtrA2 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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