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TNIP3 Antibody

TNIP3 Antibody

Item no.	OAPB00941
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Oncology Food Safety Drugs Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Aging & Neurological Disorders Antibodies By Cell Type Hematology Lymphoma Myeloma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Western Blot ELISA Autophagy Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Verstrepen L, Carpentier I, Verhelst K, et al. Abins: A20 binding inhibitors of NFÎºB and apoptosis signaling. Biochem. Pharmacol.2009; 78:105-14.;Bouwmeester T, Bauch A, Ruffner H, et al. A physical and functional map of the human TNFÎ±/NFÎºB signal transduction pathway. Nat. Cell Biol.2004; 6:97-105.;Wullaert A, Verstrepen L, Van Huffel S, et al. LIND/Abin-3 is a novel lipopolysaccharide-inducible inhibitor of NFÎºB activation. J. Biol. Chem.2007; 282:81-90.;Weaver BK, Bohn E, Judd BA, et al. Abin-3: a molecular basis for species divergence in interleukin-10-induced anti-inflammatory actions. Mol. Cell. Biol.2007; 27:4603-16.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A20-binding inhibitor of NF-kappa-B activation 3;ABIN-3;ABIN-3 beta;LIND;Listeria induced;listeria-induced gene protein;TNFAIP3-interacting protein 3;TNFAIP3-interacting protein 3 beta;TNIP3 beta.
Similar products	ABIN3
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	ABIN3 antibody can be used for detection of ABIN3 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	TNIP3
Gene Fullname	TNFAIP3 interacting protein 3
Product format	Liquid. ABIN3 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	ABIN3 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
Nucleotide accession_num	NM_001128843.2; NM_001244764.1; NM_024873.5
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_079149
Protein name	TNFAIP3-interacting protein 3\|TNFAIP3-interacting protein 3 isoform 1 [Homo sapiens]
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	ABIN3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ABIN3. The immunogen is located within the last 50 amino acids of ABIN3.
Homology	Human; Mouse
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 11/27/2025

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