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ORAI1 Antibody

ORAI1 Antibody

Item no.	OAPB01360
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Cardiovascular Research Myocardial Infarction Primary Antibodies Immunostaining
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Conjugate/Tag	Unconjugated
Citations	Lewis RS. Calcium signaling mechanisms in T lymphocytes. Annu. Rev. Immunol. 2001; 19:497-521.;Feske S, Gwack Y, Prakriya M, et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 2006; 441:179-85.;Soboloff J, Spassova MA, Dziadek MA, et al. Calcium signals mediated by STIM and Orai proteins â€“ a new paradigm in inter-organelle communication. Biochim. Biophys. Acta. 2006; 1763:1161-8.;
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	calcium release-activated calcium channel protein 1;calcium release-activated calcium modulator 1;CRACM1;IMD9;ORAT1;protein orai-1;TAM2;TMEM142A;transmembrane protein 142A.
Similar products	ORAI1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Manufacturer - Host	ORAI1 monoclonal antibody was raised in mouse. Please use anti-mouse secondary antibodies.
Shipping Temperature	Wet Ice
Molecular Weight	Predicted: 33 kDa Observed: 56 kDa
Manufacturer - Application Additional Information	ORAI1 antibody can be used for detection of ORAI1 by Western blot at 1 â€“ 2 ug/mL. (Optimal dilution should be determined by user)
Gene symbol	ORAI1
Gene Fullname	ORAI calcium release-activated calcium modulator 1
Product format	Liquid. ORAI1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	ORAI1 monoclonal antibody can be stored at 4C, stable for one year.
Description of target	Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 (PubMed:16582901, PubMed:16645049, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:19249086, PubMed:23307288, PubMed:24351972, PubMed:24591628, PubMed:28219928). CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed:16582901).
Protein name	Calcium release-activated calcium channel protein 1
Clonality	Monoclonal
Purification	Protein A Purified
Immunogen	Mouse monoclonal ORAI1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ORAI1.
Homology	Human; Mouse; Rat
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 12/25/2025

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