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MACROD1 Peptide - N-terminal region (AAP68610)

MACROD1 Peptide - N-terminal region (AAP68610)

Item no.	AAP68610
Manufacturer	AVIVA Systems Biology
Amount	100ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Peptides & Proteins Western Blot Peptides By Organ Uterine, Ovarian & Cervical Cancer
Type	Peptides
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LRP16
Similar products	MACROD1
Available
Description	This is a synthetic peptide designed for use in combination with anti-MACROD1 Antibody (ARP68610_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	MACROD1
Protein size	325
Molecular weight	36kDa
Product format	Lyophilized powder
Gene id	28992
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target	MACROD1 deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. It plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen and may play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. It could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction and could be involved in invasive growth by down-regulating CDH1 in endometrial cancer cells. MACROD1 enhances ESR1-mediated transcription activity.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AAP68610-datasheet.pdf

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Amount: 100ug

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Delivery expected until 9/25/2025

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