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b NGF Protein (OPPA00511)

b NGF Protein (OPPA00511)

Manufacturer	AVIVA Systems Biology
Category	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	other
Format	The protein was lyophilized from a 0.2 um filtered solution in 30mM sodium acetate pH=5.5 containing 1% HSA. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Amount	5ug
Host	Hamster
Item no.	OPPA00511
eClass 6.1	34160400
eClass 9.0	42020190
Available
Description	Nerve Growth Factor-beta Human Recombinant produced in CHO is a noncovalently disulfide linked homodimer, glycosylated, polypeptide chain (Ser122-Arg239) containing 2 identical 118 amino acids and having a molecular mass of 26.5 kDa.
Gene symbol	b NGF CHO
Protein name	Beta-nerve growth factor
Product format	The protein was lyophilized from a 0.2Aum filtered solution in 20mM PB and 250mM NaCl, pH 7.0. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Gene id	4803
Reconstitution and storage	It is recommended to reconstitute the lyophilized NGF-b in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Lyophilized Nerve Growth Factor b although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution Nerve Growth Factor-beta should be stored at 4C between 2-7 days and for future use below -18C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Description of target	NGF-beta has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
Biological activity	The ED₅₀, calculated by its ability to stimulate chick E9 DRG neurite outgrowth was found to be < 1.0 ng/ml, corresponding to a specific activity of > 1 x 10⁶ units/mg.
Purity	Greater than 95.0% as determined by (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 5ug

available

Delivery expected until 5/30/2024