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SCF Protein (OPPA00540)

SCF Protein (OPPA00540)

Manufacturer	AVIVA Systems Biology
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Proteins
Specific against	other
Format	Lyophilized from a concentrated (1mg/ml) solution in water containing 10mM Sodium phosphate buffer pH=6.5. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Amount	2ug
Host	E.coli
Item no.	OPPA00540
eClass 6.1	34160400
eClass 9.0	42020190
Available
Gene symbol	mSCF
Protein name	Kit ligand
Molecular weight	18 kDa
Product format	Lyophilized from a concentrated solution in water containing 0.02% NaHCO₃ Physical Appearance: Sterile filtered white freeze-dried powder
Gene id	17311
Reconstitution and storage	It is recommended to reconstitute the lyophilized Stem Cell Factor in sterile 18M-omega-cm H₂O not less than 100 ug/mL, which can be further diluted to other aqueous solutions. Lyophilized KIT ligand although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution SCF should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Description of target	Stem cell factor / KIT ligand (SCF) is a cytokine which binds CD117(c-Kit). SCF is also known as "steel factor" or "c-kit ligand". SCF exists in two forms, cell surface bound SCF and soluble (or free) SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases. SCF is a growth factor important for the survival, proliferation, and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. One of its roles is to change the BFU-E (burst-forming unit-erythroid) cells, which are the earliest erythrocyte precursors in the erythrocytic series, into the CFU-E (colony-forming unit-erythroid).
Purification	Purified by proprietary chromatographic techniques.
Biological activity	The ED₅₀ as determined by the dose-dependent stimulation of Human TF-1 cell line is <10 ng/ml, corresponding to a Specific Activity of 1x10⁵ IU/mg.
Purity	Greater than 98.0% as determined by (a) Analysis by SEC-HPLC (b) Analysis by SDS-PAGE

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2ug

available

Delivery expected until 6/13/2024