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IL 13 Protein (OPPA00637)

IL 13 Protein (OPPA00637)

Manufacturer	AVIVA Systems Biology
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines
Type	Proteins
Specific against	other
Format	The protein (1mg/ml) was lyophilized with no additives. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Amount	2ug
Host	E.coli
Item no.	OPPA00637
eClass 6.1	34160400
eClass 9.0	42020190
Available
Gene symbol	IL-13
Protein name	Interleukin-13
Product format	The protein (1mg/ml) was lyophilized with no additives. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Gene id	16163
Reconstitution and storage	Reconstitution: It is recommended to reconstitute the lyophilized Interleukin 13 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Storage: Lyophilized Interleukin-13 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution IL13 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
Description of target	IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
Purification	The IL-13 is purified by proprietary chromatographic techniques.
Biological activity	The ED₅₀ range=4 ng/ml, corresponding to a specific activity of 250, 000IU/mg as determined by the dose dependent proliferation of TF-1 cells.
Purity	Greater than 95% as determined by SDS-PAGE.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2ug

available

Delivery expected until 5/30/2024