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ENSA Protein (OPPA02085)

ENSA Protein (OPPA02085)

Manufacturer	AVIVA Systems Biology
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	other
Format	The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT and 10% glycerol. Physical appearance: Sterile filtered colorless solution.
Amount	5ug
Host	E.coli
Item no.	OPPA02085
eClass 6.1	34160400
eClass 9.0	42020190
Available
Gene symbol	ENSA
Protein name	Alpha-endosulfine
Product format	The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT and 10% glycerol. Physical appearance: Sterile filtered colorless solution.
Gene id	2029
Reconstitution and storage	Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Description of target	ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K(ATP) channel currents by inhibiting sulfonylurea from binding to the receptor and thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein (ARPP) family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, and endocrine tissues.
Purification	The ENSA is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Purity	Greater than 90.0% as determined by SDS-PAGE.
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5ug

available

Delivery expected until 5/30/2024