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CDKN1A Polyclonal Antibody

CDKN1A Polyclonal Antibody

Manufacturer	Biomatik
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma Cell Biology Cell Status Apoptosis Senescence Primary Antibodies By Organ Lung Cancer
Type	Antibody Polyclonal
Specific against	Human
Amount	50ug
Host	Rabbit
Item no.	BM-CAC08304-50ug
Targets	CDKN1A
eClass 6.1	32160702
eClass 9.0	32160702
Available
Clonality	Polyclonal
Isotype info	Recombinant Human Cyclin-dependent kinase inhibitor 1 protein (2-164AA)
Immunogen	ELISA, IHC, IF; Recommended dilution: IHC:1:1000-1:2000, IF:1:200-1:500
Conjugation	Unconjugated
Alternative Names	CDK-interacting protein 1, Melanoma differentiation-associated protein 6, p21, CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1
UniProt ID	P38936
Purification	>95%, Protein G purified
Storage	-20°C
Expiry Date	1 year
Shipping Condition	Ice packs
Comments	Conjugation service and the corresponding secondary antibody are available.
Technical Notes	May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
Restriction	For research use only. Not for diagnostic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 5/30/2024