Comparison

Cytokeratin 5 (S573) polyclonal antibody

Manufacturer Bioworld Technology, Inc
Category
Type Antibody Polyclonal
Specific against Human, Mouse, Rat
Applications WB, IF, IHC
Amount 100ul
Host Rabbit
Item no. BS1208-100
eClass 6.1 32160702
eClass 9.0 32160702
Available
Swiss-Prot
P13647
Application all
WB: 1:500ca.1:1000
IHC: 1:50ca.1:200
IF: 1:50ca.1:200
Background
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin 5 gene (KRT5) have been shown to result in the autosomal dominant disorder epidermolysis bullosa (EB).
Product
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Purification and Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Specificity
Cytokeratin 5 (S573) pAb detects endogenous levels of Cytokeratin 5 protein.
IHC
Immunohistochemistry (IHC) analyzes of Cytokeratin 5 (S573) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
BiowMW
ca. 62 kDa
Note
For research use only, not for use in diagnostic procedure.
Alternative Name
Keratin, type II cytoskeletal 5, 58 kDa cytokeratin, Cytokeratin-5, Cytokeratin5, Short name=CK-5, CK5, Keratin-5, Keratin5, Keratin 5, Short name=K5, Type-II keratin Kb5, KRT5
Immunogen
Synthetic peptide, corresponding to amino acids 550-600 of Human Cytokeratin 5.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ul
Available: In stock
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