Comparison

Anti-TEF-1 TEAD1 Antibody European Partner

Item no. BOS-A03263
Manufacturer Boster
Amount 100 ul
Category
Format Liquid
Applications WB, IF, IHC, ICC, CHIP
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Alias Transcriptional enhancer factor TEF-1,NTEF-1,Protein GT-IIC,TEA domain family member 1,TEAD-1,Transcription factor 13,TCF-13,TEAD1,TCF13,TEF1
Available
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight
47946 MW
Clonality
Polyclonal
Application Details
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
ChIP: 1:20-1:50
Gene Name
TEAD1
Gene Full Name
Transcriptional enhancer factor TEF-1
Immunogen
A synthetic peptide of human TEAD1(NP_068780.2).
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration
1 mg/ml
Protein Name
Transcriptional enhancer factor TEF-1
Protein Function
Transcription factor which plays a key role in the Hippo
signaling pathway, a pathway involved in organ size control and
tumor suppression by restricting proliferation and promoting
apoptosis. The core of this pathway is composed of a kinase
cascade wherein MST1/MST2, in complex with its regulatory protein
SAV1, phosphorylates and activates LATS1/2 in complex with its
regulatory protein MOB1, which in turn phosphorylates and
inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene
expression of YAP1 and WWTR1/TAZ, thereby regulating cell
proliferation, migration and epithelial mesenchymal transition
(EMT) induction. Binds specifically and cooperatively to the SPH
and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates
transcription in vivo in a cell-specific manner. The activation
function appears to be mediated by a limiting cell-specific
transcriptional intermediary factor (TIF). Involved in cardiac
development. Binds to the M-CAT motif.
Subcellular Localization
Nucleus.
Description
Boster Bio Anti-TEF-1 TEAD1 Antibody catalog # A03263. Tested in WB, IHC, ICC/IF, ChIP applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Preferentially expressed in skeletal muscle.
Lower levels in pancreas, placenta, and heart.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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